Invention Grant
US08697692B2 Pyrrolo [3,2-c] pyridine-4-one 2-indolinone protein kinase inhibitors
有权
吡咯并[3,2-c]吡啶-4-酮2-二氢吲哚酮蛋白激酶抑制剂
![Pyrrolo [3,2-c] pyridine-4-one 2-indolinone protein kinase inhibitors](/docs/US/2014-04-15/US08697692B2/abs.jpg.600x600.jpg)
- Patent Title: Pyrrolo [3,2-c] pyridine-4-one 2-indolinone protein kinase inhibitors
- Patent Title (中): 吡咯并[3,2-c]吡啶-4-酮2-二氢吲哚酮蛋白激酶抑制剂
-
Application No.: US13196391Application Date: 2011-08-02
-
Publication No.: US08697692B2Publication Date: 2014-04-15
- Inventor: Peng Cho Tang , Yidong Su , Lei Zhang , Lu Xiao
- Applicant: Peng Cho Tang , Yidong Su , Lei Zhang , Lu Xiao
- Applicant Address: CN Shanghai
- Assignee: Shanghai Hengrui Pharmaceutical Co., Ltd.
- Current Assignee: Shanghai Hengrui Pharmaceutical Co., Ltd.
- Current Assignee Address: CN Shanghai
- Agency: Rothwell, Figg, Ernst & Manbeck P.C.
- Priority: CN200610003229 20060127; CN200610065001 20060315; CN200610122000 20060830
- Main IPC: A61K31/535
- IPC: A61K31/535 ; A01N43/90 ; A61K31/519 ; A01N43/42 ; A61K31/44
![Pyrrolo [3,2-c] pyridine-4-one 2-indolinone protein kinase inhibitors](/abs-image/US/2014/04/15/US08697692B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to pyrrolo[3,2-c]pyridine-4-one 2-indolinone compounds of Formula (I) and their pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8 X, Y and have the meaning cited in the specification. Also disclosed are the pharmaceutical compositions containing the foregoing compounds, methods for the preparation and pharmaceutical use thereof, particularly as protein kinase inhibitors. Formula (I).
Public/Granted literature
- US20120058107A1 PYRROLO [3,2-C] PYRIDINE-4-ONE 2-INDOLINONE PROTEIN KINASE INHIBITORS Public/Granted day:2012-03-08
Information query
