Invention Grant
US08697720B2 Substituted phenylether-thienopyridone compounds with antibacterial activity
有权
取代的苯基醚 - 噻吩并吡酮化合物具有抗菌活性
- Patent Title: Substituted phenylether-thienopyridone compounds with antibacterial activity
- Patent Title (中): 取代的苯基醚 - 噻吩并吡酮化合物具有抗菌活性
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Application No.: US11853589Application Date: 2007-09-11
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Publication No.: US08697720B2Publication Date: 2014-04-15
- Inventor: Joseph Guiles , Xicheng Sun , Nebojsa Janjic , Sarah Strong
- Applicant: Joseph Guiles , Xicheng Sun , Nebojsa Janjic , Sarah Strong
- Applicant Address: US CO Boulder
- Assignee: Crestone, Inc.
- Current Assignee: Crestone, Inc.
- Current Assignee Address: US CO Boulder
- Agency: Swanson & Bratschun, LLC
- Main IPC: A01N43/42
- IPC: A01N43/42 ; A61K31/44 ; C07D513/02 ; C07D515/02 ; C07D215/00
Abstract:
Novel bicyclic heteroaromatic compounds are provided that are inhibitors of bacterial methionyl tRNA synthetase (MetRS). Compounds of the invention generally have a left hand side phenylether constituent and a right hand side thienopyridone constituent. Also disclosed are methods for their preparation and their use in therapy as antibacterial agents, particularly as anti-Clostridium difficile agents.
Public/Granted literature
- US20080227808A1 Substituted Phenylether-Thienopyridone Compounds With Antibacterial Activity Public/Granted day:2008-09-18
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