Invention Grant
- Patent Title: Medical application of lipid derivatives of dopamine and the methods of their production
- Patent Title (中): 多巴胺脂质衍生物的医学应用及其制备方法
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Application No.: US13303935Application Date: 2011-11-23
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Publication No.: US08697898B2Publication Date: 2014-04-15
- Inventor: Mieczyslaw Pokorski , Dominika Zajac , Zbigniew Czarnocki , Piotr Roszkowski
- Applicant: Mieczyslaw Pokorski , Dominika Zajac , Zbigniew Czarnocki , Piotr Roszkowski
- Applicant Address: PL Warsaw PL Warsaw
- Assignee: Instytut Medycyny Doswiadczalnej i Klinicznej im. M. Mossakowskiego PAN,Uniwersytet Warszawski
- Current Assignee: Instytut Medycyny Doswiadczalnej i Klinicznej im. M. Mossakowskiego PAN,Uniwersytet Warszawski
- Current Assignee Address: PL Warsaw PL Warsaw
- Agency: Brooks Kushman P.C.
- Main IPC: C07C231/00
- IPC: C07C231/00 ; C07C233/00

Abstract:
A medical application of N-oleoyl-dopamine and 3′-O-methyl-N-oleoyl-dopamine for the production of a medication for treatment or prophylaxis of disturbances or states due to deficiency of dopamine, preferably chosen from the group covering oxygen deficiencies (hypoxia) in anesthetized and awake mammals, breathing with atmospheric oxygen (normoxia), for the respiratory responses to hypoxia in mammals, lack of dopamine binding to the membrane system in the mammalian brain, disturbances in metabolic pathways of dopamine metabolism, states of dopamine deficiencies provoked by morbid or genetic factors as well as under condition connected to the physiological process of aging of the organism, through the systemic introduction of the compound to the mammalian organism. A method of production of 3′-O-methyl-N-oleoyl-dopamine in vitro is also disclosed.
Public/Granted literature
- US20130131361A1 NOVEL MEDICAL APPLICATION OF LIPID DERIVATIVES OF DOPAMINE AND THE METHODS OF THEIR PRODUCTION Public/Granted day:2013-05-23
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