Invention Grant
US08697898B2 Medical application of lipid derivatives of dopamine and the methods of their production 有权
多巴胺脂质衍生物的医学应用及其制备方法

Medical application of lipid derivatives of dopamine and the methods of their production
Abstract:
A medical application of N-oleoyl-dopamine and 3′-O-methyl-N-oleoyl-dopamine for the production of a medication for treatment or prophylaxis of disturbances or states due to deficiency of dopamine, preferably chosen from the group covering oxygen deficiencies (hypoxia) in anesthetized and awake mammals, breathing with atmospheric oxygen (normoxia), for the respiratory responses to hypoxia in mammals, lack of dopamine binding to the membrane system in the mammalian brain, disturbances in metabolic pathways of dopamine metabolism, states of dopamine deficiencies provoked by morbid or genetic factors as well as under condition connected to the physiological process of aging of the organism, through the systemic introduction of the compound to the mammalian organism. A method of production of 3′-O-methyl-N-oleoyl-dopamine in vitro is also disclosed.
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