Invention Grant
US08700150B2 Implantable neurostimulator for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction with bounded titration
有权
用于提供电刺激颈部迷走神经用于治疗慢性心脏功能障碍的有限滴定的植入式神经刺激器
- Patent Title: Implantable neurostimulator for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction with bounded titration
- Patent Title (中): 用于提供电刺激颈部迷走神经用于治疗慢性心脏功能障碍的有限滴定的植入式神经刺激器
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Application No.: US13931961Application Date: 2013-06-30
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Publication No.: US08700150B2Publication Date: 2014-04-15
- Inventor: Imad Libbus , Badri Amurthur , Bruce H. Kenknight
- Applicant: Cyberonics, Inc.
- Applicant Address: US TX Houston
- Assignee: Cyberonics, Inc.
- Current Assignee: Cyberonics, Inc.
- Current Assignee Address: US TX Houston
- Agency: Cyberonics, Inc.
- Main IPC: A61N1/365
- IPC: A61N1/365

Abstract:
A system for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction with bounded titration is provided. The system includes a patient-operable external controller to transmit a plurality of unique signals. The system further includes an implantable neurostimulator, which includes a pulse generator to deliver electrical therapeutic stimulation tuned to restore autonomic balance through continuously-cycling, intermittent and periodic electrical pulses that result in creation and propagation (in both afferent and efferent directions) of action potentials within the cervical vagus nerve of a patient through a pair of helical electrodes via an electrically coupled nerve stimulation therapy lead. The neurostimulator also includes a recordable memory storing an autotitration operating mode that includes a maximum stimulation intensity and is configured to increase an intensity of the delivered electrical therapeutic stimulation up to a level not exceeding the maximum stimulation intensity upon receipt of one of the unique signals.
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