A data processing system 2 includes an instruction decoder 22 responsive to polynomial divide instructions DIVL.PN to generate control signals that control processing circuitry 26 to perform a polynomial division operation. The denominator polynomial is represented by a denominator value stored within a register with an assumption that the highest degree term of the polynomial always has a coefficient of “1” such that this coefficient need not be stored within the register storing the denominator value and accordingly the denominator polynomial may have a degree one higher than would be possible with the bit space within the register storing the denominator value alone. The polynomial divide instruction returns a quotient value and a remainder value respectively representing the quotient polynomial and the remainder polynomial.