Systems and methods for treating a subsurface formation are described herein. Some method include providing heat to a section of the formation from a plurality of heaters located in the formation, allowing the heat to transfer from the heaters to heat a portion of the section to a selected temperature to generate an in situ deasphalting fluid in the section, contacting at least a portion of the in situ deasphalting fluid with hydrocarbons in the section to remove at least some asphaltenes from the hydrocarbons in the section, and producing at least a portion of the deasphalted hydrocarbons from the formation. The in situ deasphalting fluid may include hydrocarbons having a boiling range distribution between 35° C. and 260° C. at 0.101 MPa. A majority of the hydrocarbons in the section may have a boiling point greater than 260° C. at 0.101 MPa.