The present invention includes a surgical stapler having a curved end-effector which is configured to deploy staples in at least one curved staple line. In various embodiments, the surgical stapler includes a staple cartridge, an anvil, and a cutting member having a cutting surface wherein the cutting member is relatively movable with respect to the anvil and the staple cartridge. In one embodiment, the staple cartridge can be configured to deploy staples along different, non-parallel axes. As a result, the staples can be deployed in a significantly curved staple line. In various embodiments, the surgical stapler includes a flexible driver operably engaged with the cutting member to move the cutting member relative to the anvil and the staple cartridge. In these embodiments, the driver can include an elongate cross-section defined by a width and a height wherein its width is greater, and in some cases, substantially greater, than its height.