Invention Grant
- Patent Title: Beta-amyloid PET imaging agents
- Patent Title (中): β-淀粉样蛋白PET成像剂
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Application No.: US12293340Application Date: 2007-04-19
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Publication No.: US08703096B2Publication Date: 2014-04-22
- Inventor: Lisheng Cai , Victor W. Pike , Robert B. Innis
- Applicant: Lisheng Cai , Victor W. Pike , Robert B. Innis
- Applicant Address: US DC Washington
- Assignee: The United States of America as Represented by the Secretary of the Department of Health and Human Services
- Current Assignee: The United States of America as Represented by the Secretary of the Department of Health and Human Services
- Current Assignee Address: US DC Washington
- Agency: Cantor Colburn LLP
- International Application: PCT/US2007/066939 WO 20070419
- International Announcement: WO2007/124345 WO 20071101
- Main IPC: A61K51/00
- IPC: A61K51/00 ; A61M36/14 ; A61K38/00 ; A61P25/28 ; A61K31/00
Abstract:
Novel derivatives of imidazopyridinylbenzeneamines and novel derivatives of benzothiazolylbenzeneamines are disclosed that offer improved behavior when used as imaging agents for positron emission tomography of beta-amyloids. Also disclosed is a palladium-catalyzed reaction scheme under microwave conditions for aryl thioethers in general that provides a high ratio of substitution relative to reduction and can be used for the imidazopyridinylbenzeneamine derivatives as well as other compounds of related structure.
Public/Granted literature
- US20110008255A1 BETA-AMYLOID PET IMAGING AGENTS Public/Granted day:2011-01-13
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