Invention Grant
- Patent Title: Use of oncolytic herpes viruses for killing cancer stem cells
- Patent Title (中): 使用溶瘤性疱疹病毒杀死癌症干细胞
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Application No.: US12994960Application Date: 2009-05-04
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Publication No.: US08703120B2Publication Date: 2014-04-22
- Inventor: Robert Martuza , Samuel Rabkin , Hiroaki Wakimoto , Ryuichi Kanai
- Applicant: Robert Martuza , Samuel Rabkin , Hiroaki Wakimoto , Ryuichi Kanai
- Applicant Address: US MA Boston
- Assignee: The General Hospital Corporation
- Current Assignee: The General Hospital Corporation
- Current Assignee Address: US MA Boston
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2009/002735 WO 20090504
- International Announcement: WO2009/148488 WO 20091210
- Main IPC: A01N63/00
- IPC: A01N63/00 ; A01N65/00 ; A61K48/00
Abstract:
The invention, in some aspects, relates to the selective killing of cancer stem cells by oncolytic Herpes virus mediated oncolysis. In some aspects, the invention relates to methods for treating a subject having a cancer stem cell by administering to the subject an oncolytic Herpes virus. In other aspects, the invention provides methods for evaluating the efficacy of an oncolytic Herpes virus for killing cancer stem cells.
Public/Granted literature
- US20110177032A1 USE ON ONCOLYTIC HERPES VIRUSES FOR KILLING CANCER STEM CELLS Public/Granted day:2011-07-21
Information query
