Invention Grant
- Patent Title: Antibody variants
- Patent Title (中): 抗体变体
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Application No.: US13052982Application Date: 2011-03-21
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Publication No.: US08703133B2Publication Date: 2014-04-22
- Inventor: Yvonne M. Chen , Henry B. Lowman , Yves Muller
- Applicant: Yvonne M. Chen , Henry B. Lowman , Yves Muller
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent Connie Wong
- Main IPC: A61K39/395
- IPC: A61K39/395
Abstract:
Antibody variants of parent antibodies are disclosed which have one or more amino acids inserted in a hypervariable region of the parent antibody and a binding affinity for a target antigen which is at least about two fold stronger than the binding affinity of the parent antibody for the antigen.
Public/Granted literature
- US20110182895A1 ANTIBODY VARIANTS Public/Granted day:2011-07-28
Information query
