Invention Grant
US08703196B2 Pharmaceutical compositions of dispersions of amorphous drugs mixed with polymers
有权
与聚合物混合的无定形药物的分散体的药物组合物
- Patent Title: Pharmaceutical compositions of dispersions of amorphous drugs mixed with polymers
- Patent Title (中): 与聚合物混合的无定形药物的分散体的药物组合物
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Application No.: US13563536Application Date: 2012-07-31
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Publication No.: US08703196B2Publication Date: 2014-04-22
- Inventor: Walter C. Babcock , William J. Curatolo , Dwayne T. Friesen , Rodney J. Ketner , Julian B. Lo , James A. S. Nightingale , Ravi M. Shanker , James B. West
- Applicant: Walter C. Babcock , William J. Curatolo , Dwayne T. Friesen , Rodney J. Ketner , Julian B. Lo , James A. S. Nightingale , Ravi M. Shanker , James B. West
- Applicant Address: US OR Bend
- Assignee: Bend Research, Inc.
- Current Assignee: Bend Research, Inc.
- Current Assignee Address: US OR Bend
- Agency: Chernoff Vilhauer McClung & Stenzel LLP
- Main IPC: A61K9/14
- IPC: A61K9/14 ; A61K47/38
Abstract:
A pharmaceutical composition comprises a dispersion comprising a low-solubility drug and a matrix combined with a concentration-enhancing polymer. At least a major portion of the drug is amorphous in the dispersion. The compositions improve the stability of the drug in the dispersion, and/or the concentration of drug in a use environment.
Public/Granted literature
- US20120295988A1 Pharmaceutical Compositions of Dispersions of Amorphous Drugs Mixed with Polymers Public/Granted day:2012-11-22
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