Invention Grant
- Patent Title: Coated tablets
- Patent Title (中): 涂层片剂
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Application No.: US11492373Application Date: 2006-07-24
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Publication No.: US08703202B2Publication Date: 2014-04-22
- Inventor: Michael Vachon , Mishra K. Awadhesh , Robert A. Snow , Pol-Henri Guivarc'h
- Applicant: Michael Vachon , Mishra K. Awadhesh , Robert A. Snow , Pol-Henri Guivarc'h
- Applicant Address: CH Muttenz
- Assignee: Jagotec AG
- Current Assignee: Jagotec AG
- Current Assignee Address: CH Muttenz
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Agent Muriel Liberto, Esq.
- Main IPC: A61K9/14
- IPC: A61K9/14 ; A61K9/16 ; A61K9/20 ; A61K31/19 ; A61K31/216 ; A61K9/48

Abstract:
Disclosed is a pharmaceutically acceptable oral dosage form comprising fenofibrate, phospholipid, a buffer salt, a water-soluble bulking agent selected from maltodextrin, mannitol, and combinations thereof, a cellulosic additive, beads or crystals of a pharmaceutically acceptable water-soluble excipient support material, a polyvinylpyrrolidone or crospovidone, croscarmellose sodium, granular mannitol, sodium dodecyl sulfate, silicon dioxide, and a stearate, wherein the fenofibrate is in the form of microparticles, and wherein at least a portion of the phospholipid is coated on the surfaces of the fenofibrate microparticles, the phospholipid coated microparticles are embedded in a matrix comprising the water-soluble bulking agent, phospholipid that is not coated on the microparticles, the buffer salt and the cellulosic additive, and the matrix is coated on up to 100% of the surfaces of the beads or crystals of the excipient support material.
Public/Granted literature
- US20060257494A1 Coated tablets Public/Granted day:2006-11-16
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