Invention Grant
US08703485B2 Germ cells having inactivated endogenous immunoglobulin genes, and transgenic animals derived therefrom
有权
具有灭活的内源免疫球蛋白基因的生殖细胞和从其衍生的转基因动物
- Patent Title: Germ cells having inactivated endogenous immunoglobulin genes, and transgenic animals derived therefrom
- Patent Title (中): 具有灭活的内源免疫球蛋白基因的生殖细胞和从其衍生的转基因动物
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Application No.: US12130818Application Date: 2008-05-30
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Publication No.: US08703485B2Publication Date: 2014-04-22
- Inventor: Roland Buelow
- Applicant: Roland Buelow
- Applicant Address: US CA San Carlos
- Assignee: OMT, Inc.
- Current Assignee: OMT, Inc.
- Current Assignee Address: US CA San Carlos
- Agency: Arnold & Porter LLP
- Agent Todd Lorenz
- Main IPC: C12N5/00
- IPC: C12N5/00 ; A01K67/027
Abstract:
The invention relates to transgenic animals lacking endogenous Ig and capable of producing transgenic antibodies, as well as methods of making the same. The invention further relates to methods for producing transgenic antibodies in such animals, and transgenic antibodies so produced.
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