Invention Grant
- Patent Title: Inhibitors of F18+ E coli binding
- Patent Title (中): F18 +大肠杆菌结合抑制剂
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Application No.: US13122002Application Date: 2009-09-30
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Publication No.: US08703722B2Publication Date: 2014-04-22
- Inventor: Annelies Coddens , Eric Cox , Susann Eva Teneberg
- Applicant: Annelies Coddens , Eric Cox , Susann Eva Teneberg
- Applicant Address: BE Gent
- Assignee: Universiteit Gent
- Current Assignee: Universiteit Gent
- Current Assignee Address: BE Gent
- Agency: Dinsmore & Shohl LLP
- Priority: GB0817908.7 20081001
- International Application: PCT/EP2009/062699 WO 20090930
- International Announcement: WO2010/037785 WO 20100408
- Main IPC: A61K31/702
- IPC: A61K31/702 ; A61K31/715 ; A61K47/30 ; A61K47/42 ; A61P31/04 ; C08B37/00 ; C07K1/107 ; C07K14/765 ; C07H3/06 ; C07H15/04

Abstract:
The present invention relates to blood group A/B/H determinant on Type 1 Core glycosphingolipids chains as recognition point for the FedF protein of F18-fimbriated Enterotoxigenic and verotoxinogenic Escherichia coli and the use of compounds comprising such determinants for the treatment of F18+ E. coli infections in pigs and in screening methods.
Public/Granted literature
- US20110306574A1 INHIBITORS OF F18+ E COLI BINDING Public/Granted day:2011-12-15
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