Invention Grant
US08703952B2 Synthesis of 9-(arylalkyl)-1,2,3,4-tetrahydro-γ-carboline and analogues and intermediates
有权
9-(芳基烷基)-1,2,3,4-四氢-γ-咔啉及其类似物和中间体的合成
- Patent Title: Synthesis of 9-(arylalkyl)-1,2,3,4-tetrahydro-γ-carboline and analogues and intermediates
- Patent Title (中): 9-(芳基烷基)-1,2,3,4-四氢-γ-咔啉及其类似物和中间体的合成
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Application No.: US13133900Application Date: 2009-12-11
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Publication No.: US08703952B2Publication Date: 2014-04-22
- Inventor: Craig Williamson , John Mervyn David Storey
- Applicant: Craig Williamson , John Mervyn David Storey
- Applicant Address: SG Singapore
- Assignee: WisTa Laboratories Ltd.
- Current Assignee: WisTa Laboratories Ltd.
- Current Assignee Address: SG Singapore
- Agency: Foley & Lardner LLP
- International Application: PCT/GB2009/002873 WO 20091211
- International Announcement: WO2010/067085 WO 20100617
- Main IPC: C07D491/00
- IPC: C07D491/00 ; A61K31/44

Abstract:
The present invention pertains generally to methods of preparing certain 9-(arylalkyl)-1,2,3,4-tetrahydro-γ-carboline compounds and their analogues, and especially to methods of preparing dimebon. The present invention also pertains to methods of preparing certain intermediate compounds which find use in the synthesis of the 9-(arylalkyl)-1,2,3,4-tetrahydro-γ-carboline compounds.
Public/Granted literature
- US20110245504A1 SYNTHESIS OF 9-(ARYLALKYL)-1,2,3,4-TETRAHYDRO-y-CARBOLINE AND ANALOGUES AND INTERMEDIATES Public/Granted day:2011-10-06
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