A memory access technique, in accordance with one embodiment of the present invention, includes caching page size data for use in accessing a set-associative translation lookaside buffer (TLB). The technique utilizes a translation lookaside buffer data structure that includes a page size table and a translation lookaside buffer. Upon receipt of a memory access request a page size is looked-up in the page size table utilizing the page directory index in the virtual address. A set index is calculated utilizing the page size. A given set of entries is then looked-up in the translation lookaside buffer utilizing the set index. The virtual address is compared to each TLB entry in the given set. If the comparison results in a TLB hit, the physical address is received from the matching TLB entry.