Invention Grant
US08710016B2 ActRIIB proteins and variants and uses therefore relating to utrophin induction for muscular dystrophy therapy
有权
因此ActRIIB蛋白质和变体和用途涉及肌营养不良症治疗的utrophin诱导
- Patent Title: ActRIIB proteins and variants and uses therefore relating to utrophin induction for muscular dystrophy therapy
- Patent Title (中): 因此ActRIIB蛋白质和变体和用途涉及肌营养不良症治疗的utrophin诱导
-
Application No.: US12948411Application Date: 2010-11-17
-
Publication No.: US08710016B2Publication Date: 2014-04-29
- Inventor: Jasbir Seehra , Jennifer Lachey
- Applicant: Jasbir Seehra , Jennifer Lachey
- Applicant Address: US MA Cambridge
- Assignee: Acceleron Pharma, Inc.
- Current Assignee: Acceleron Pharma, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Ropes & Gray LLP
- Main IPC: A61K38/18
- IPC: A61K38/18 ; C07K14/475
Abstract:
In certain aspects, the present invention provides compositions and methods for inducing utrophin expression in muscle with an ActRIIB protein as therapy for muscular dystrophy. The present invention also provides methods of screening compounds that modulate activity of an ActRIIB protein and/or an ActRIIB ligand.
Public/Granted literature
Information query
IPC分类:
