The present invention relates to a medicament container holder arrangement comprising a medicament container holder 16 and a medicament container 18 wherein the medicament container holder 16 is provided with distally arranged support surfaces 25 for flanges 24 arranged on a distal part of the medicament container 18 to be placed in said medicament container holder 16, which medicament container 18 is arranged with a needle shield 20 to the proximal end thereof, wherein said needle shield 20 has a diameter generally equal or larger than the diameter of said medicament container 18, wherein said medicament container holder arrangement further comprises holders arranged on the container holder for holding said medicament container 18 around a proximal shoulder portion 22 thereof and a resilient support element 23 arranged between the flanges 24 and the support surfaces 25 whereby the holders and the resilient support element 23 absorb and spread forces between the medicament container and the container holder.