A sleeve for a protective garment, such as a medical gown, includes a knit, woven, or non-woven layer and a seamless layer that are laminated together. The knit, woven, or non-woven layer can be a circularly knit seamless layer, or alternatively can have seams. The seamless layer can be water or vapor impermeable or resistant so as to prevent microorganisms, pathogens, liquids, or other substances from passing through the sleeve.