Invention Grant
US08715653B2 Modulation of Rhamm (CD168) for selective adipose tissue development
有权
调节Rhamm（CD168）用于选择性脂肪组织发育
- Patent Title: Modulation of Rhamm (CD168) for selective adipose tissue development
- Patent Title (中): 调节Rhamm（CD168）用于选择性脂肪组织发育
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Application No.: US12515405Application Date: 2007-11-21
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Publication No.: US08715653B2Publication Date: 2014-05-06
- Inventor: Eva A. Turley , Mina J. Bissell
- Applicant: Eva A. Turley , Mina J. Bissell
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Weaver Austin Villeneuve & Sampson LLP
- Agent Tom Hunter
- International Application: PCT/US2007/085453 WO 20071121
- International Announcement: WO2008/140586 WO 20081120
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K39/00
Abstract:
Herein is described the methods and compositions for modulation of Rhamm, also known as CD 186, and its effects on wound repair, muscle differentiation, bone density and adipogeneisis through its ability to regulate mesenchymal stem cell differentiation. Compositions and methods are provided for blocking Rhamm function for selectively increasing subcutaneous, but not, visceral fat. Compositions and methods for modulating Rhamm in wound repair are also described.
Public/Granted literature
- US20100143382A1 MODULATION OF RHAMM (CD168) FOR SELECTIVE ADIPOSE TISSUE DEVELOPMENT Public/Granted day:2010-06-10
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