Invention Grant
US08715674B2 Antibodies binding to an intracellular PRL-1 or PRL-3 polypeptide
有权
结合细胞内PRL-1或PRL-3多肽的抗体
- Patent Title: Antibodies binding to an intracellular PRL-1 or PRL-3 polypeptide
- Patent Title (中): 结合细胞内PRL-1或PRL-3多肽的抗体
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Application No.: US12598442Application Date: 2008-05-03
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Publication No.: US08715674B2Publication Date: 2014-05-06
- Inventor: Qi Zeng
- Applicant: Qi Zeng
- Applicant Address: SG Singapore
- Assignee: Agency for Science, Technology and Research (A*Star)
- Current Assignee: Agency for Science, Technology and Research (A*Star)
- Current Assignee Address: SG Singapore
- Agency: Nixon Peabody LLP
- Agent David S. Resnick; Mark J. FitzGerald
- International Application: PCT/SG2008/000161 WO 20080503
- International Announcement: WO2008/136774 WO 20081113
- Main IPC: A61K39/395
- IPC: A61K39/395

Abstract:
We provide an antibody capable of binding to an intracellular PRL-1 or PRL-3 polypeptide, in which the antibody is capable of binding to an epitope bound by antibody 269, antibody 223 or antibody 318. Such anti-PRL antibodies may be capable of binding to intracellular PRL-1 or PRL-3. They may be suitable for use as therapies against cancer or metastasis thereof, or in clinical diagnosis to identify PRL-3 or PRL-1 positive patients.
Public/Granted literature
- US20110206657A1 ANTIBODIES BINDING TO AN INTRACELLULAR PRL-1 OR PRL-3 POLYPEPTIDE Public/Granted day:2011-08-25
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