Invention Grant
US08715699B2 Amino acid conjugates of quetiapine, process for making and using the same
有权
喹硫平的氨基酸缀合物，其制备和使用方法
- Patent Title: Amino acid conjugates of quetiapine, process for making and using the same
- Patent Title (中): 喹硫平的氨基酸缀合物，其制备和使用方法
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Application No.: US13518981Application Date: 2010-12-22
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Publication No.: US08715699B2Publication Date: 2014-05-06
- Inventor: Travis Mickle , Sven Guenther , Sanjib Bera
- Applicant: Travis Mickle , Sven Guenther , Sanjib Bera
- Applicant Address: US IA Coralville
- Assignee: KemPharm, Inc.
- Current Assignee: KemPharm, Inc.
- Current Assignee Address: US IA Coralville
- Agency: McAndrews, Held & Malloy, Ltd.
- International Application: PCT/US2010/061853 WO 20101222
- International Announcement: WO2011/082076 WO 20110707
- Main IPC: A61K31/554
- IPC: A61K31/554 ; A61K9/00 ; A61K33/00 ; C07D417/04 ; A61P25/18 ; A61P25/24 ; A61P25/22
Abstract:
The presently described technology provides a novel class of prodrugs of quetiapine that can be synthesized by chemically conjugating amino acids to quetiapine. The present technology also provides methods of treating patients, pharmaceutical compositions and methods of synthesizing conjugates of the present technology.
Public/Granted literature
- US20120276168A1 AMINO ACID CONJUGATES OF QUETIAPINE, PROCESS FOR MAKING AND USING THE SAME Public/Granted day:2012-11-01
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