Invention Grant
- Patent Title: Assay methods using nicking endonucleases
- Patent Title (中): 使用切口内切核酸酶的测定方法
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Application No.: US12891343Application Date: 2010-09-27
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Publication No.: US08715933B2Publication Date: 2014-05-06
- Inventor: John S. Oliver
- Applicant: John S. Oliver
- Applicant Address: US RI Providence
- Assignee: Nabsys, Inc.
- Current Assignee: Nabsys, Inc.
- Current Assignee Address: US RI Providence
- Agency: Goodwin Procter LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
Assay methods and apparatus for the analysis of biopolymers are disclosed. The assays employ nicking endonucleases to enable the generation of flaps on target biomolecules which are detected in nanopore or fluidic channel devices. Identification of flap locations enables a map of the target biomolecule to be derived.
Public/Granted literature
- US20120074925A1 Assay Methods Using Nicking Endonucleases Public/Granted day:2012-03-29
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