Invention Grant
- Patent Title: Enzymatically catalyzed method of preparing mono-acylated polyols
- Patent Title (中): 单酰化多元醇的酶催化方法
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Application No.: US13496342Application Date: 2010-09-16
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Publication No.: US08715970B2Publication Date: 2014-05-06
- Inventor: Bernhard Hauer , Cecilia Kvarnström Branneby , Karl Hult , Anders Magnusson , Anders Hamberg
- Applicant: Bernhard Hauer , Cecilia Kvarnström Branneby , Karl Hult , Anders Magnusson , Anders Hamberg
- Applicant Address: DE
- Assignee: BASF SE
- Current Assignee: BASF SE
- Current Assignee Address: DE
- Agency: Novak Druce Connolly Bove + Quigg LLP
- Priority: EP09170458 20090916
- International Application: PCT/EP2010/063645 WO 20100916
- International Announcement: WO2011/033039 WO 20110324
- Main IPC: C12P7/62
- IPC: C12P7/62 ; C12N1/21
Abstract:
The present invention relates to a biocatalytic method of preparing a mono-acylated polyol catalyzed by triacylglycerol lipase mutants, as for example derived from Candida antarctica lipase B (CALB); a biocatalytic method of enantioselectively preparing an asymmetric mono-acylated polyol, catalyzed by the same enzyme mutants; as well as the use of a mutated triacylglycerol lipase in a method of preparing mono-acylated polyols. The invention also provides novel mutants, coding sequences thereof, and recombinant microorganisms carrying said coding sequences.
Public/Granted literature
- US20120171738A1 ENZYMATICALLY CATALYZED METHOD OF PREPARING MONO-ACYLATED POLYOLS Public/Granted day:2012-07-05
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