Invention Grant
US08715985B2 Clostridium histolyticum recombinant collagenases and method for the manufacture thereof
有权
Clostridium histolyticum重组胶原酶及其制备方法
- Patent Title: Clostridium histolyticum recombinant collagenases and method for the manufacture thereof
- Patent Title (中): Clostridium histolyticum重组胶原酶及其制备方法
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Application No.: US13515203Application Date: 2010-12-15
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Publication No.: US08715985B2Publication Date: 2014-05-06
- Inventor: Federico Bertuzzi , Angela Cuttitta , Giulio Ghersi , Salvatore Mazzola , Monica Salamone , Gregorio Seidita
- Applicant: Federico Bertuzzi , Angela Cuttitta , Giulio Ghersi , Salvatore Mazzola , Monica Salamone , Gregorio Seidita
- Applicant Address: IT Campobello
- Assignee: Abiel S.R.L.
- Current Assignee: Abiel S.R.L.
- Current Assignee Address: IT Campobello
- Agency: Nixon & Vanderhye PC
- Priority: ITRM2009A0661 20091215
- International Application: PCT/IB2010/055840 WO 20101215
- International Announcement: WO2011/073925 WO 20110623
- Main IPC: C12N9/00
- IPC: C12N9/00 ; C12N9/48
Abstract:
The present invention relates to the production of recombinant collagenases, and in particular describes a method for the production of recombinant Clostridium histolyticum collagenases CoI characterized by a yield higher than approximately 140 mg/l of culture of said collagenases in soluble and biologically active form, collagenases produced by this method, compositions comprising these collagenases and the use thereof.
Public/Granted literature
- US20120252092A1 CLOSTRIDIUM HISTOLYTICUM RECOMBINANT COLLAGENASES AND METHOD FOR THE MANUFACTURE THEREOF Public/Granted day:2012-10-04
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