Invention Grant
- Patent Title: Adenovirus E1A fragments for use in anti-cancer therapies
- Patent Title (中): 用于抗癌疗法的腺病毒E1A片段
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Application No.: US13552407Application Date: 2012-07-18
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Publication No.: US08716014B2Publication Date: 2014-05-06
- Inventor: Maurice Green , Paul M. Loewenstein
- Applicant: Maurice Green , Paul M. Loewenstein
- Applicant Address: US MO St. Louis
- Assignee: Saint Louis University
- Current Assignee: Saint Louis University
- Current Assignee Address: US MO St. Louis
- Agency: Parker Highlander PLLC
- Main IPC: A61K39/235
- IPC: A61K39/235
Abstract:
The present invention relates to an improved cancer therapy comprising co-administration with the E1A 1-80 transcription-repression domain activity. In addition, E1A 1-80 can act as a monotherapy against cancers that express elevated HER2/Neu or in combination with anti-HER2/Neu, chemo- or radiotherapeutic treatments.
Public/Granted literature
- US20130023481A1 Adenovirus E1A Fragments for Use in Anti-Cancer Therapies Public/Granted day:2013-01-24
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