Invention Grant
- Patent Title: Reprogrammation of eukaryotic cells with engineered microvesicles
- Patent Title (中): 用工程微泡重新编程真核细胞
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Application No.: US13505934Application Date: 2010-11-10
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Publication No.: US08716020B2Publication Date: 2014-05-06
- Inventor: Philippe Mangeot , Vincent Lotteau , Marc Peschanski , Mathilde Girard
- Applicant: Philippe Mangeot , Vincent Lotteau , Marc Peschanski , Mathilde Girard
- Applicant Address: FR Paris
- Assignee: INSERM (Institut National de la Sante et de la Recherche Medicale)
- Current Assignee: INSERM (Institut National de la Sante et de la Recherche Medicale)
- Current Assignee Address: FR Paris
- Agency: McAndrews, Held & Malloy Ltd.
- Priority: EP09306092 20091113
- International Application: PCT/EP2010/067225 WO 20101110
- International Announcement: WO2011/058064 WO 20110519
- Main IPC: C12N5/07
- IPC: C12N5/07 ; C12N5/073
Abstract:
The present invention relates to a non-genetic, detergent-free, bacteria-free method for reprogramming a eukaryotic cell, in particular for obtaining induced pluripotent stem cells (iPS), by using engineered microvesicles carrying at least one reprogramming transcription factor, wherein said engineered microvesicles are virus-free.
Public/Granted literature
- US20130034900A1 REPROGRAMMATION OF EUKARYOTIC CELLS WITH ENGINEERED MICROVESICLES Public/Granted day:2013-02-07
Information query
