Invention Grant
US08716220B2 Leptin compositions and methods for treating progressive cognitive function disorders resulting from accumulation of neurofibrillary tangles and amyloid beta
失效
瘦素组合物和治疗由神经原纤维缠结和淀粉样蛋白β积累引起的进行性认知功能障碍的方法
- Patent Title: Leptin compositions and methods for treating progressive cognitive function disorders resulting from accumulation of neurofibrillary tangles and amyloid beta
- Patent Title (中): 瘦素组合物和治疗由神经原纤维缠结和淀粉样蛋白β积累引起的进行性认知功能障碍的方法
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Application No.: US12612613Application Date: 2009-11-04
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Publication No.: US08716220B2Publication Date: 2014-05-06
- Inventor: Nikolaos Tezapsidis , Steven J. Greco , Mark Smith
- Applicant: Nikolaos Tezapsidis , Steven J. Greco , Mark Smith
- Main IPC: A61K38/22
- IPC: A61K38/22
Abstract:
The present disclosure provides compositions containing a leptin product and methods of clinical therapy and diagnostic methods for progressive cognitive disorders. According to one aspect, the described invention provides a method for treating a progressive cognitive disorder. According to another aspect, the described invention provides a method for improving resilience of cognitive function in a subject in need thereof. According to another aspect, the described invention provides a method for identifying an effective therapeutic agent for treating a progressive cognitive dysfunction disease or disorder that results from at least one of accumulation of Aβ, hyperphosphorylation of tau, or accumulation of neurofibrillary tangles.
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