Invention Grant
US08716253B2 Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes
有权
通过位置化学变化调节免疫刺激性寡核苷酸类似物的免疫刺激活性
- Patent Title: Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes
- Patent Title (中): 通过位置化学变化调节免疫刺激性寡核苷酸类似物的免疫刺激活性
-
Application No.: US10694075Application Date: 2003-10-27
-
Publication No.: US08716253B2Publication Date: 2014-05-06
- Inventor: Ekambar R. Kandimalla , Qiuyan Zhao , Dong Yu , Sudhir Agrawal
- Applicant: Ekambar R. Kandimalla , Qiuyan Zhao , Dong Yu , Sudhir Agrawal
- Applicant Address: US MA Cambridge
- Assignee: Idera Pharmaceuticals, Inc.
- Current Assignee: Idera Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C07H21/02 ; A01N43/04 ; A61K39/00 ; A61K39/38
Abstract:
The invention relates to the therapeutic use of oligonucleotides or oligonucleotide analogs as immunostimulatory agents in immunotherapy applications. The invention provides methods for enhancing the immune response caused by immunostimulatory oligonucleotide compounds.
Public/Granted literature
Information query
