Invention Grant
- Patent Title: Bicyclic antibiotics
- Patent Title (中): 双环抗生素
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Application No.: US13145323Application Date: 2010-01-21
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Publication No.: US08716280B2Publication Date: 2014-05-06
- Inventor: Berangere Gaucher , Franck Hubert Danel , Patrick Roussel
- Applicant: Berangere Gaucher , Franck Hubert Danel , Patrick Roussel
- Applicant Address: CH Basel
- Assignee: Basilea Pharmaceutica AG
- Current Assignee: Basilea Pharmaceutica AG
- Current Assignee Address: CH Basel
- Priority: EP09151027 20090121
- International Application: PCT/EP2010/050684 WO 20100121
- International Announcement: WO2010/084152 WO 20100729
- Main IPC: C07D498/04
- IPC: C07D498/04 ; C07D413/04 ; A61K31/5415 ; A61K31/5383

Abstract:
The antibacterial compound of formula I wherein X1, X3; X4 and X6, each independently of the others, represents a nitrogen atom or CR2, with the proviso that at least one of X1, X3; X4 and X6 represents a nitrogen atom; X2 represents C—H, C—(C1-C6alkyl), C—(C1-C6alkoxy), C-halogen, C—COOH; X5 represents C—H or C—(C1-C6alkyl), C-halogen; A1, A2, A3, R1 and R4 represent various substituents, G represents aryl or heteroaryl, which is unsubstituted or substituted which compounds show good activity against pathogenic bacteria.
Public/Granted literature
- US20120040957A1 Novel Bicyclic Antibiotics Public/Granted day:2012-02-16
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