Invention Grant
- Patent Title: Type III secretion inhibitors, analogs and uses thereof
- Patent Title (中): III型分泌抑制剂，类似物及其用途
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Application No.: US12742043Application Date: 2009-04-01
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Publication No.: US08716283B2Publication Date: 2014-05-06
- Inventor: Jon Goguen , Ning Pan , Kyungae Lee
- Applicant: Jon Goguen , Ning Pan , Kyungae Lee
- Applicant Address: US MA Boston US MA Cambridge
- Assignee: University of Massachusetts,President and Fellows of Harvard College
- Current Assignee: University of Massachusetts,President and Fellows of Harvard College
- Current Assignee Address: US MA Boston US MA Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2009/002022 WO 20090401
- International Announcement: WO2009/145829 WO 20091203
- Main IPC: A61K31/44
- IPC: A61K31/44 ; C07D213/84
Abstract:
The invention, in some aspects, relates to compounds and compositions useful for inhibiting Type III secretion systems in pathogenic bacteria, such as Yersinia Pestis. In some aspects, the invention relates to methods for discovering inhibitors of the Type III secretion system and uses of such inhibitors in the treatment and prevention of disease.
Public/Granted literature
- US20110034463A1 TYPE III SECRETION INHIBITORS, ANALOGS AND USES THEREOF Public/Granted day:2011-02-10
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