Invention Grant
US08716288B2 Composition comprising benproperine derivatives as active ingredients for preventing and treating angiogenesis-related diseases
有权
包含benproperine衍生物作为预防和治疗血管发生相关疾病的活性成分的组合物
- Patent Title: Composition comprising benproperine derivatives as active ingredients for preventing and treating angiogenesis-related diseases
- Patent Title (中): 包含benproperine衍生物作为预防和治疗血管发生相关疾病的活性成分的组合物
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Application No.: US13891837Application Date: 2013-05-10
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Publication No.: US08716288B2Publication Date: 2014-05-06
- Inventor: Byoung Mog Kwon , Dong Cho Han , Dae Seop Shin , Young Min Han
- Applicant: Byoung Mog Kwon , Dong Cho Han , Dae Seop Shin , Young Min Han
- Applicant Address: KR Daejon
- Assignee: Korea Research Institute of Bioscience and Biotechnology
- Current Assignee: Korea Research Institute of Bioscience and Biotechnology
- Current Assignee Address: KR Daejon
- Agency: Cooper & Dunham LLP
- Agent John P. White
- Priority: KR10-2010-0112343 20101111
- Main IPC: A61K31/5377
- IPC: A61K31/5377
Abstract:
The present invention relates to a novel pharmaceutical composition of benproperine derivatives for preventing and treating angiogenesis-related diseases. The benproperine derivatives and pharmaceutically acceptable salts thereof according to the present invention inhibit cancer cell migration and the angiogenesis of vascular endothelial cells, and therefore can be effectively used not only as an anticancer agent, but also as an agent for preventing and treating diseases caused by abnormal angiogenesis, such as diabetic retinopathy and corneal transplant rejection.
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