Inhibitors of protein kinases

Invention Grant

US08716296B2 Inhibitors of protein kinases 失效

Title translation: 蛋白激酶抑制剂

Patent Title: Inhibitors of protein kinases
Patent Title (中): 蛋白激酶抑制剂
Application No.: US12226286

Application Date: 2008-10-13
Publication No.: US08716296B2

Publication Date: 2014-05-06
Inventor: Hans Allgeier , Martin Augustin , Anke Müller , Lutz Zeitlmann , Andreas Marquardt , Michael A. Pleiss , Ulrich Heiser , André Johannes Niestroj
Applicant: Hans Allgeier , Martin Augustin , Anke Müller , Lutz Zeitlmann , Andreas Marquardt , Michael A. Pleiss , Ulrich Heiser , André Johannes Niestroj
Applicant Address: DE Martinsried
Assignee: Ingenium Pharmaceuticals GmbH
Current Assignee: Ingenium Pharmaceuticals GmbH
Current Assignee Address: DE Martinsried
Agency: Olson & Cepuritis, Ltd.
International Application: PCT/EP2008/063715 WO 20081013
International Announcement: WO2009/047359 WO 20090416
Main IPC: A01N43/54
IPC: A01N43/54 ; C07D401/00

Abstract:

Compounds of general formula (I): are useful as inhibitors of cyclin dependent kinases such as CDK9.

Abstract(Chinese):

通式（I）的化合物：可用作细胞周期依赖性激酶如CDK9的抑制剂。

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IPC分类:

A	人类生活必需
A01	农业；林业；畜牧业；狩猎；诱捕；捕鱼
A01N	人体、动植物体或其局部的保存（食品或粮食的保存入A23）；杀生剂，例如作为消毒剂，作为农药或作为除草剂（杀灭或防止不期望生物体的生长或繁殖的医用、牙科用或梳妆用的配制品入A61K）；害虫驱避剂或引诱剂；植物生长调节剂
A01N43/00	含有杂环化合物的杀生剂、害虫驱避剂或引诱剂，或植物生长调节剂（含有环酐，环状亚胺的化合物入A01N37/00；含有分子式Xm……CnNCC的化合物，即仅含1个杂环，其中m≥1和n≥0及NCC是未取代的或是烷基取代的吡咯烷、哌啶、吗啉、硫代吗啉、哌嗪或带有4个或更多CH2基的聚亚甲基亚胺的化合物入A01N33/00至A01N41/12；含环丙烷羧酸或其衍生物，如具有杂环的酯入A01N53/00）
A01N43/48	.具有带两个氮原子作为仅有的环杂原子的环
A01N43/54	..1,3二嗪；氢化1,3二嗪