Invention Grant
- Patent Title: Analogs of thalidomide as potential angiogenesis inhibitors
- Patent Title (中): 沙利度胺类似物作为潜在的血管生成抑制剂
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Application No.: US11880404Application Date: 2007-07-19
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Publication No.: US08716315B2Publication Date: 2014-05-06
- Inventor: William D. Figg , Kurt Eger , Uwe Teubert , Michael Weiss , Michael Guetschow , Thomas Hecker , Sunna Hauschildt
- Applicant: William D. Figg , Kurt Eger , Uwe Teubert , Michael Weiss , Michael Guetschow , Thomas Hecker , Sunna Hauschildt
- Applicant Address: US DC Washington
- Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
- Current Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
- Current Assignee Address: US DC Washington
- Agency: Klarquist Sparkman, LLP
- Main IPC: A61K31/445
- IPC: A61K31/445
Abstract:
A number of thalidomide metabolites having superior anti-angiogenic properties have now been isolated and identified. In addition, thalidomide analogs that mimic the effects of the isolated and identified active thalidomide metabolites, and variations of such thalidomide analogs, have been developed. Such thalidomide analog compounds show enhanced potency in the inhibition of undesirable angiogenesis without the undesirable effects of administration of thalidomide.
Public/Granted literature
- US20070293519A1 Analogs of thalidomide as potential angiogenesis inhibitors Public/Granted day:2007-12-20
Information query
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