Invention Grant
- Patent Title: Methods for dosing an orally active 1,2,4-oxadiazole
- Patent Title (中): 口服有效的1,2,4-恶二唑的给药方法
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Application No.: US11918114Application Date: 2006-04-06
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Publication No.: US08716321B2Publication Date: 2014-05-06
- Inventor: Samit Hirawat , Langdon Miller
- Applicant: Samit Hirawat , Langdon Miller
- Applicant Address: US NJ South Plainfield
- Assignee: PTC Therapeutics, Inc.
- Current Assignee: PTC Therapeutics, Inc.
- Current Assignee Address: US NJ South Plainfield
- Agency: Jones Day
- International Application: PCT/US2006/012887 WO 20060406
- International Announcement: WO2006/110483 WO 20061019
- Main IPC: A61K31/4245
- IPC: A61K31/4245 ; A61P3/10 ; A61P7/00 ; A61P9/00 ; A61P11/00 ; A61P25/00 ; A61P25/28 ; A61P35/00
Abstract:
The present invention relates to specific doses of and dosing regimens for using a 1,2,4-oxadiazole benzoic acid compound in treating or preventing diseases associated with nonsense mutations. In particular, the invention relates to specific doses and dosing regimens for the use of 3-[5-(2-fluoro-phenyl)-[1,2,4]oxadiazol-3-yl]-benzoic acid in mammals having diseases associated with nonsense mutations.
Public/Granted literature
- US20090149513A1 Compositions of an Orally Active 1,2,4-Oxadiazole for Nonsense Mutation Suppression Therapy Public/Granted day:2009-06-11
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