Invention Grant
US08716334B2 Substituted cyclohexylidene-ethylidene-octahydro-indene compounds
有权
取代的亚环己基 - 亚乙基 - 八氢 - 茚化合物
- Patent Title: Substituted cyclohexylidene-ethylidene-octahydro-indene compounds
- Patent Title (中): 取代的亚环己基 - 亚乙基 - 八氢 - 茚化合物
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Application No.: US12993262Application Date: 2009-06-16
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Publication No.: US08716334B2Publication Date: 2014-05-06
- Inventor: Shimon Ben Shabat , Amnou Sintov
- Applicant: Shimon Ben Shabat , Amnou Sintov
- Applicant Address: IL Beer Sheva
- Assignee: Ben Gurion University of the Negev Research and Development Authority
- Current Assignee: Ben Gurion University of the Negev Research and Development Authority
- Current Assignee Address: IL Beer Sheva
- Agency: Pearl Cohen Zedek Latzer Baratz LLP
- Agent Mark S. Cohen
- International Application: PCT/IL2009/000597 WO 20090616
- International Announcement: WO2009/153782 WO 20091223
- Main IPC: A61K31/336
- IPC: A61K31/336 ; C07D317/02 ; C07D303/32
Abstract:
Novel substituted cyclohexylidene-ethylidene-octahydro-indene compounds and compositions comprising the same are described. The compounds exhibit profound anti-proliferative effects, in comparison to other compounds known for their anti-cancer and anti-hyperproliferative ability. Methods of use of such compounds and compositions are described for treating a variety of cancers, inflammatory and other hyperproliferative diseases and disorders.
Public/Granted literature
- US20110098350A1 SUBSTITUTED CYCLOHEXYLIDENE-ETHYLIDENE-OCTAHYDRO-INDENE COMPOUNDS Public/Granted day:2011-04-28
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