Invention Grant
- Patent Title: Biopolymer conjugates comprising an interleukin-11 analog
- Patent Title (中): 包含白细胞介素-11类似物的生物聚合物缀合物
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Application No.: US12589511Application Date: 2009-08-21
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Publication No.: US08716446B2Publication Date: 2014-05-06
- Inventor: Yuni Jung , Seong-Hyun Ho , Myung-Ok Park , Myoung-Suk Kim
- Applicant: Yuni Jung , Seong-Hyun Ho , Myung-Ok Park , Myoung-Suk Kim
- Applicant Address: KR Seoul KR Seoul
- Assignee: Biopolymed Inc.,Viromed Co., Ltd.
- Current Assignee: Biopolymed Inc.,Viromed Co., Ltd.
- Current Assignee Address: KR Seoul KR Seoul
- Agency: Sughrue Mion, PLLC
- Priority: KR10-2008-0083070 20080825
- Main IPC: C07K14/54
- IPC: C07K14/54 ; A61K38/20 ; A61K47/10 ; A61K38/00
Abstract:
The present invention provides for biopolymer conjugates of an IL-11 analog (mIL-11) and a biocompatible polymer. The mIL-11 of the invention displays an enhanced resistance to acidolysis and shows increased stability as compared to rhIL-11. The conjugates of the present invention are characterized by a longer serum half-life and exhibit essentially no loss of activity as compared to the corresponding unconjugated mIL-11.
Public/Granted literature
- US20100098658A1 Biopolymer Conjugates Comprising an Interleukin-11 Analog Public/Granted day:2010-04-22
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