Invention Grant
- Patent Title: Fully human antibodies against human 4-1BB
- Patent Title (中): 全人类抗人4-1BB抗体
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Application No.: US13368710Application Date: 2012-02-08
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Publication No.: US08716452B2Publication Date: 2014-05-06
- Inventor: Maria Jure-Kunkel , Laura J. Hefta , Marc Santoro , Subinay Ganguly , Edward L. Halk
- Applicant: Maria Jure-Kunkel , Laura J. Hefta , Marc Santoro , Subinay Ganguly , Edward L. Halk
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Paul D. Golian
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/00
Abstract:
Fully human antibodies and antigen-binding portions thereof that bind to human 4-1BB and that allow binding of human 4-1BB to a human 4-1BB ligand. In one aspect, the antibody is an IgG4 antibody. Also provided is a method for treating a disease in a subject comprising administering a therapeutically effective amount of the antibody to said subject.
Public/Granted literature
- US20120141494A1 FULLY HUMAN ANTIBODIES AGAINST HUMAN 4-1BB Public/Granted day:2012-06-07
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