Invention Grant
- Patent Title: Methods and devices for nucleic acid synthesis
- Patent Title (中): 用于核酸合成的方法和装置
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Application No.: US13038714Application Date: 2011-03-02
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Publication No.: US08716467B2Publication Date: 2014-05-06
- Inventor: Joseph Jacobson
- Applicant: Joseph Jacobson
- Applicant Address: US MA Cambridge
- Assignee: Gen9, Inc.
- Current Assignee: Gen9, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Greenberg Traurig, LLP
- Agent Jennifer A. Camacho; Natalie Salem
- Main IPC: C07H21/00
- IPC: C07H21/00

Abstract:
Disclosed are devices and methods to synthesize polynucleotides and libraries of polynucleotides such as libraries of oligonucleotides. In exemplary embodiments, the device includes a support having a plurality of features. Each feature contains a plurality of oligonucleotides. Within each feature, each of the plurality of oligonucleotides includes an identical predetermined subunit sequence of X nucleosides and a degenerate sequence of Y nucleosides. A predetermined combination of a subset of the features can be used to produce a polynucleotide having a predetermined sequence of Z nucleosides.
Public/Granted literature
- US20110217738A1 Methods and Devices for Nucleic Acid Synthesis Public/Granted day:2011-09-08
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