Invention Grant
- Patent Title: Compounds that are ERK inhibitors
- Patent Title (中): ERK抑制剂的化合物
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Application No.: US12918099Application Date: 2009-02-19
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Publication No.: US08716483B2Publication Date: 2014-05-06
- Inventor: Alan B. Cooper , Yang Nan , Yongqi Deng , Gerald W. Shipps, Jr. , Neng-Yang Shih , Hugh Y. Zhu , Jagdish A. Desai , James J-S Wang , Sunil Paliwal , Hon-Chung Tsui , Sobhana Babu Boga , Abdul-Basit Alhassan , Xiaolei Gao , Liang Zhu , Ahmed Samatar
- Applicant: Alan B. Cooper , Yang Nan , Yongqi Deng , Gerald W. Shipps, Jr. , Neng-Yang Shih , Hugh Y. Zhu , Jagdish A. Desai , James J-S Wang , Sunil Paliwal , Hon-Chung Tsui , Sobhana Babu Boga , Abdul-Basit Alhassan , Xiaolei Gao , Liang Zhu , Ahmed Samatar
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Richard S. Parr; Laura M. Ginkel
- International Application: PCT/US2009/034447 WO 20090219
- International Announcement: WO2009/105500 WO 20090827
- Main IPC: C07D401/04
- IPC: C07D401/04 ; A61K31/444
Abstract:
Disclosed are the ERK inhibitors of formula 1.0: and the pharmaceutically acceptable salts, and solvates thereof. Q is a tetrahydropyridinyl ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.
Public/Granted literature
- US20110189192A1 NOVEL COMPOUNDS THAT ARE ERK INHIBITORS Public/Granted day:2011-08-04
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