An opto-isolated amplifier and method are disclosed. The amplifier includes an input node configured to receive an input to be amplified. A pair of opto-isolators are coupled between an input node and an output node. The opto-isolators are configured to create gain between the input node and the output node. An amplification stage is coupled to the opto-isolators. The amplification stage includes an input coupled to the output node and an output configured to generate an amplified output. The opto-isolator outputs may be configured to generate a difference current. The input of the amplification stage may have a high impedance compared to an impedance at the output node, the difference current being directed at the high input impedance input of the amplification stage to generate a gained voltage.