A food preparation cutting board for cutting and storing food stuff in isolated compartments adjacent to the cutting board preferably includes a cutting board including a plurality of openings formed along a perimeter thereof, and a plurality of food containers removably interfitted within the openings respectively such that the food containers are juxtaposed adjacent to the perimeter of the cutting board. The food containers are fixedly engaged with the cutting board when the food containers are disposed within the openings respectively. Such food containers are capable of may be interchangeably oriented at an upright position and an inverted position relative to the cutting board. In this manner, the food containers are adapted to receive food stuff directly from the cutting board. Furthermore, a user is able to expand the surface area of the cutting board and/or conveniently slide food stuff into the food containers directly from the cutting board.