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US08722018B2 Method for preparing nanoparticles covered with a gem-bisphosphonate stabilizing layer coupled to hydrophilic distribution ligands 有权
制备纳米颗粒的方法，该纳米粒子与偶联到亲水性配位配体上的偕二膦酸盐稳定层覆盖

  • Patent Title: Method for preparing nanoparticles covered with a gem-bisphosphonate stabilizing layer coupled to hydrophilic distribution ligands
  • Patent Title (中): 制备纳米颗粒的方法，该纳米粒子与偶联到亲水性配位配体上的偕二膦酸盐稳定层覆盖
  • Application No.: US12681378
    Application Date: 2008-10-06
  • Publication No.: US08722018B2
    Publication Date: 2014-05-13
  • Inventor: Marc Port , Olivier Rousseaux
  • Applicant: Marc Port , Olivier Rousseaux
  • Applicant Address: FR Villepinte
  • Assignee: Guerbet
  • Current Assignee: Guerbet
  • Current Assignee Address: FR Villepinte
  • Agency: Young & Thompson
  • Priority: FR0758103 20071005
  • International Application: PCT/FR2008/051802 WO 20081006
  • International Announcement: WO2009/053596 WO 20090430
  • Main IPC: A61B5/055
  • IPC: A61B5/055
Method for preparing nanoparticles covered with a gem-bisphosphonate stabilizing layer coupled to hydrophilic distribution ligands
Abstract:
A novel method for preparing nanoparticles for medical imaging, including a metal core, an organic stabilizing layer containing gem-bisphosphonate compounds and at least one hydrophilic biodistribution ligand.
Abstract(Chinese):

一种用于制备用于医学成像的纳米颗粒的新方法，包括金属芯，含有双膦酸化合物的有机稳定层和至少一种亲水性生物分布配体。

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