Invention Grant
- Patent Title: Human monoclonal antibodies protective against bubonic plague
- Patent Title (中): 人类单克隆抗体，防止瘟疫
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Application No.: US13260413Application Date: 2010-04-08
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Publication No.: US08722046B2Publication Date: 2014-05-13
- Inventor: Kei Amemiya , Dimiter S. Dimitrov , Xiaodong Xiao
- Applicant: Kei Amemiya , Dimiter S. Dimitrov , Xiaodong Xiao
- Applicant Address: US DC Washington
- Assignee: The United States of America as Represented by the Secretary of the Army
- Current Assignee: The United States of America as Represented by the Secretary of the Army
- Current Assignee Address: US DC Washington
- Agent Elizabeth Arwine
- International Application: PCT/US2010/001051 WO 20100408
- International Announcement: WO2010/117455 WO 20101014
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C12P21/08 ; A61K39/40
Abstract:
In this application are described fully human monoclonal antibodies which specifically recognize F1 or V antigen of Y. pestis and epitopes recognized by these monoclonal antibodies. Also provided are mixtures of antibodies of the present invention, as well as methods of using individual antibodies or mixtures thereof for the detection, prevention, and/or therapeutical treatment of plague infections in vitro and in vivo.
Public/Granted literature
- US20120114656A1 Human Monoclonal Antibodies Protective Against Bubonic Plague Public/Granted day:2012-05-10
Information query
