Invention Grant
- Patent Title: Fluorescent nanocrystals encapsulated in an inorganic shell
- Patent Title (中): 封装在无机壳中的荧光纳米晶体
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Application No.: US12933610Application Date: 2009-03-19
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Publication No.: US08722095B2Publication Date: 2014-05-13
- Inventor: Alain Ibanez , Noélie Marcellin , Elisabeth Djurado , Cécile Philippot
- Applicant: Alain Ibanez , Noélie Marcellin , Elisabeth Djurado , Cécile Philippot
- Applicant Address: FR Paris FR Grenoble
- Assignee: Centre National de la Recherche Scientifique—CNRS,Institut National Polytechnique de Grenoble
- Current Assignee: Centre National de la Recherche Scientifique—CNRS,Institut National Polytechnique de Grenoble
- Current Assignee Address: FR Paris FR Grenoble
- Agency: Arent Fox LLP
- Priority: FR0851830 20080321
- International Application: PCT/FR2009/000294 WO 20090319
- International Announcement: WO2009/125086 WO 20091015
- Main IPC: A61K9/50
- IPC: A61K9/50 ; A61K9/51

Abstract:
The present invention relates to a method of preparing hybrid organo/mineral nanoparticles comprising an organic fluorescent crystalline core encapsulated in an inorganic shell, and to nanoparticles that can be obtained by said method. The method of the present invention comprises the following steps: (i) a sol-gel mixture able to be obtained by a process comprising the addition, in at least one organic solvent, in the presence of water, of a fluorescent organic compound and at least one metal alkoxide is sprayed; (ii) the sprayed sol-gel mixture is dried, by evaporating the solvent and the water that are present in the sol-gel mixture. The nanoparticles of the present invention can be used for example as a tracer in medical imaging or as a chemical sensor.
Public/Granted literature
- US20110110864A1 FLUORESCENT NANOCRYSTALS ENCAPSULATED IN AN INORGANIC SHELL Public/Granted day:2011-05-12
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