Invention Grant
US08722340B2 JAB1 as a prognostic marker and a therapeutic target for human cancer
有权
JAB1作为预后标志物和人类癌症治疗靶点
- Patent Title: JAB1 as a prognostic marker and a therapeutic target for human cancer
- Patent Title (中): JAB1作为预后标志物和人类癌症治疗靶点
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Application No.: US11874838Application Date: 2007-10-18
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Publication No.: US08722340B2Publication Date: 2014-05-13
- Inventor: Francois Claret
- Applicant: Francois Claret
- Applicant Address: US TX Austin
- Assignee: Board of Regents, The University of Texas System
- Current Assignee: Board of Regents, The University of Texas System
- Current Assignee Address: US TX Austin
- Agency: Parker Highlander PLLC
- Main IPC: G01N33/53
- IPC: G01N33/53
Abstract:
Methods of diagnosing and prognosticating the development of human cancers, such as breast cancer, colon cancer, and pancreatic cancer, are provided. The diagnostic and prognostic methods include the detection and/or quantifying of the amount of expression of JAB1 in human cells, particularly in relation to the amount of p27 or c-Jun. In addition, methods for reducing the expression of JAB1 protein in cells and inhibiting its interaction with p27 or c-Jun, for example, are provided.
Public/Granted literature
- US20090148868A1 JAB1 AS A PROGNOSTIC MARKER AND A THERAPEUTIC TARGET FOR HUMAN CANCER Public/Granted day:2009-06-11
Information query
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