Invention Grant
- Patent Title: Detecting PAX2 for the diagnosis of breast cancer
- Patent Title (中): 检测PAX2用于诊断乳腺癌
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Application No.: US13606917Application Date: 2012-09-07
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Publication No.: US08722367B2Publication Date: 2014-05-13
- Inventor: Carlton D. Donald
- Applicant: Carlton D. Donald
- Applicant Address: US GA Atlanta
- Assignee: Phigenix, Inc.
- Current Assignee: Phigenix, Inc.
- Current Assignee Address: US GA Atlanta
- Agency: Andrews Kurth, LLP
- Agent Ping Wang
- Main IPC: C12P19/34
- IPC: C12P19/34 ; C12Q1/68
Abstract:
A method for monitoring breast conditions in a subject is disclosed. The method comprises determining a Paired Box 2 gene-to-beta defensin-1 gene (PAX2-to-DEFB1) expression ratio (the “Donald Predictive Factor” or “DPF”) in cells obtained from the breast of the subject, wherein the PAX2-to-DEFB1 expression ratio is correlated with breast conditions. Also disclosed is a kit for monitoring breast conditions and determining drug resistance.
Public/Granted literature
- US20130023424A1 DETECTING PAX2 FOR THE DIAGNOSIS OF BREAST CANCER Public/Granted day:2013-01-24
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