Invention Grant
US08722370B2 Method for producing an L-amino acid using a bacterium of the enterobacteriaceae family, having attenuated expression of gene(s) encoding peptidase
有权
使用肠杆菌科的细菌生产L-氨基酸的方法,其具有减毒的编码肽酶的基因的表达
- Patent Title: Method for producing an L-amino acid using a bacterium of the enterobacteriaceae family, having attenuated expression of gene(s) encoding peptidase
- Patent Title (中): 使用肠杆菌科的细菌生产L-氨基酸的方法,其具有减毒的编码肽酶的基因的表达
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Application No.: US13687541Application Date: 2012-11-28
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Publication No.: US08722370B2Publication Date: 2014-05-13
- Inventor: Dmitriy Vladimirovich Filippov , Tatyana Viktorovna Leonova , Elvira Borisovna Voroshilova , Mikhail Markovich Gusyatiner , Mika Moriya , Yuri Nagai , Keiko Noguchi
- Applicant: AJINOMOTO CO., INC.
- Applicant Address: JP Tokyo
- Assignee: Ajinomoto Co., Inc.
- Current Assignee: Ajinomoto Co., Inc.
- Current Assignee Address: JP Tokyo
- Agency: Cermak Nakajima LLP
- Agent Shelly Guest Cermak
- Priority: RU2010122647 20100603
- Main IPC: C12P13/10
- IPC: C12P13/10

Abstract:
The present invention provides a method for producing L-amino acids, such as L-arginine, L-citrulline, and L-lysine, using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to the genus Escherichia or Pantoea, which has been modified to attenuate expression of one or more genes, such as the pepA, pepB, and pepD genes.
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