Invention Grant
- Patent Title: FGF21 conjugates and anti-diabetic uses thereof
- Patent Title (中): FGF21缀合物及其抗糖尿病用途
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Application No.: US13289533Application Date: 2011-11-04
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Publication No.: US08722622B2Publication Date: 2014-05-13
- Inventor: Tapan Kanti Das , Tamara Shafer Hodge , Tetsuya Ishino , Nancy Jane Levin , Moorthy Sitharamaiah Suriyanarayana Palanki , Erin Kristen Parsons , Bernard Norman Violand
- Applicant: Tapan Kanti Das , Tamara Shafer Hodge , Tetsuya Ishino , Nancy Jane Levin , Moorthy Sitharamaiah Suriyanarayana Palanki , Erin Kristen Parsons , Bernard Norman Violand
- Applicant Address: IE Dun Laoghaire, County Dublin US NY New York
- Assignee: COVX Technologies Ireland, Limited,Pfizer Inc.
- Current Assignee: COVX Technologies Ireland, Limited,Pfizer Inc.
- Current Assignee Address: IE Dun Laoghaire, County Dublin US NY New York
- Agent Wendy L. Hsu
- Main IPC: A61K38/18
- IPC: A61K38/18 ; A61K39/395
Abstract:
The present invention provides a FGF21 molecule covalently attached to the combining site of an antibody via a linker, wherein the linker is covalently attached to the side chain of a linking residue within FGF21. Various uses of the compounds are provided, including methods to prevent or treat diabetes or diabetes-related conditions.
Public/Granted literature
- US20120282279A1 Anti-Diabetic Compounds Public/Granted day:2012-11-08
Information query
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