Invention Grant
US08722649B2 Alpha-chloro and alpha-bromo phosphonate analogs of lysophosphatidic acid and methods of making and using thereof
有权
溶血磷脂酸的α-氯和α-溴膦酸酯类似物及其制备和使用方法
- Patent Title: Alpha-chloro and alpha-bromo phosphonate analogs of lysophosphatidic acid and methods of making and using thereof
- Patent Title (中): 溶血磷脂酸的α-氯和α-溴膦酸酯类似物及其制备和使用方法
-
Application No.: US12664543Application Date: 2008-06-13
-
Publication No.: US08722649B2Publication Date: 2014-05-13
- Inventor: Glenn Prestwich , Gabor Tigyi , Guowei Jiang , Guanghui Yang , Joanna Gajewiak , Honglu Zhang , Xiaoyu Xu
- Applicant: Glenn Prestwich , Gabor Tigyi , Guowei Jiang , Guanghui Yang , Joanna Gajewiak , Honglu Zhang , Xiaoyu Xu
- Applicant Address: US UT Salt Lake City US TN Knoxville
- Assignee: University of Utah Research Foundation,University of Tennessee Research Foundation
- Current Assignee: University of Utah Research Foundation,University of Tennessee Research Foundation
- Current Assignee Address: US UT Salt Lake City US TN Knoxville
- Agency: Gardner, Groff, Greenwald & Villanueva, P.C.
- International Application: PCT/US2008/066934 WO 20080613
- International Announcement: WO2008/157361 WO 20081224
- Main IPC: A61K31/661
- IPC: A61K31/661 ; C07F9/10
Abstract:
Described herein is the synthesis and pharmacology of a series of α-substituted methylene phosphonate analogs, in which the α-CH2 moiety is replaced with CHCl or CHBr.
Public/Granted literature
Information query
